1. Acute intermittent porphyria is probably the most common porphyria with acute
  2. The disorder results from low levels of the enzyme responsible for the third step in heme production.
  3. Red urine
  4. Sensitivity to sunlight
  5. Blister (bulla) formation on exposure to sunlight
  6. Skin swelling (edema) on exposure to sunlight
  7. Photodermatitis
  8. Crampy abdominal pain (may be extremely severe)
  9. Constipation
  10. Vomiting
  11. Pain in the limbs
  12. Pain in the back
  13. Personality change
  14. Numbness or tingling
  15. Muscle pain
  16. Muscle weakness or paralysis
  17. During an attack, a person may also experience muscle weakness, seizures, and mental changes such as anxiety and hallucinations.
  18. Attacks are triggered by nongenetic factors such as certain drugs, alcohol, smoking, dieting or fasting, certain hormones, other illnesses, and stress.