1. Malaria typically produces a string of recurrent attacks, or paroxysms, each of which has three stages—chills, followed by fever, and then sweating.
  2. Along with chills, the person is likely to have headache, nausea, and vomiting.
  3. Within an hour or two, the person’s temperature rises, and the skin feels hot and dry. Then, as the body temperature falls, a drenching sweat begins. The person, feeling tired and weak, is likely to fall asleep.
  4. The symptoms first appear some 10 to 16 days after the infectious mosquito bite and coincide with the bursting of infected red blood cells.
  5. When many red blood cells are infected and break at the same time, malaria attacks can recur at regular time periods—every 2 days for P. vivax malaria and P. ovale, and every 3 days for P. malariae.