Systemic Lupus Erythematosus (sis-TEM-ick LOO-pus err-ah-theme-ahTOE-sus) is a chronic (long-lasting) rheumatic disease which affects joints, muscles and other parts of the body. Lupus involves inflammation (the immune system's response to kill foreign agents, virus, bacteria). Systemic lupus erythematosus involves chronic inflammation that can affect many parts of the body.

  1. Malar (MAY-lar) rash (a butterfly shaped rash over the cheeks and across the bridge of the nose)
  2. Discoid rash (scaly, disk-shaped sores on the face, neck and/or chest)
  3. Sensitivity to sunlight
  4. Oral ulcers
  5. Arthritis (pain, stiffness in joints)
  6. Serositis (inflammation of the lining around the heart, lungs, and/or abdomen, causing pain and shortness of breath)
  7. Kidney problems (protein leak)
  8. Central nervous system problems
  9. Blood problems (anemia)
  10. Problems with the immune system (risk of infection)
  11. Antinuclear antibodies (autoantibodies that react against the body's own cells)
  12. Other symptoms include: Anemia, Fatigue, Fever, Skin rash, Muscle aches, Nausea, Vomiting and diarrhea, Swollen glands Lack of appetite, Sensitivity to cold (Raynaud's phenomenon), Weight loss