Whipple's disease is a rare infectious disease that typically infects the bowel.

  1. Symptoms of Whipple's disease include darkened skin; painful, inflamed joints; diarrhea; light-colored, soft, bulky, and foul smelling stool (called steatorrhea); arthritis; abdominal pain; cough; and enlarged lymph nodes in the chest.
  2. Chest pain can occur if fluid collects in the lungs and the membranes covering the lungs, the pleura, become inflamed.
  3. People with Whipple's disease develop heart murmurs if the infection reaches the heart, and liver enlargement if the infection reaches the liver.