The following is a list of notable world figures who died on February 27.
- 1892: Louis Vuitton, French luggage maker whose designs have become increasingly popular
- 1936: Ivan Pavlov, Russian physiologist, known for "Pavlov's Dogs" experiment
- 1985: Henry Cabot Lodge, running mate to Richard Nixon in his unsuccessful bid for presidency
- 1986: Jacques Plante, Canadian hockey player, one of the greatest goalies of all time
- 1998: George H. Hitchings, American scientist, recipient of the Nobel Prize for his work in the field of medicine
- 2003: Fred Rogers, (Mister Rogers Neighborhood)