- Two medications currently are used to treat acromegaly. These drugs reduce both GH secretion and tumor size.
- Medical therapy is sometimes used to shrink large tumors before surgery. Bromocriptine (Parlodel®) in divided doses of about 20 mg daily reduces GH secretion from some pituitary tumors.
- Side effects include gastrointestinal upset, nausea, vomiting, light-headedness when standing, and nasal congestion. These side effects can be reduced or eliminated if medication is started at a very low dose at bedtime, taken with food, and gradually increased to the full therapeutic dose.
- Radiation therapy has been used both as a primary treatment and combined with surgery or drugs.
- It is usually reserved for patients who have tumor remaining after surgery. These patients often also receive medication to lower GH levels.
- This treatment lowers GH levels by about 50 percent over 2 to 5 years. Patients monitored for more than 5 years show significant further improvement.
Add Your Comment
You must be logged in to post a comment.