The combinations of these herbal medicines like Rhizoma seu Radix Notopterygii, Radix Puerariae, Radix Angelicae Sinensis, Caulis Spatholobi, Rhizoma Ligustici Chuanxiong, Radix Arnebiae seu Lithospermi, Radix Ledebouriellae, Radix Ophiopogonis, Flos Carthami are used to cure systemic sclerosis.