The following is a list of notable world figures who died on October 21st.

  1. 1125 - Cosmas of Prague, Bohemian writer
  2. 1221 - Alix of Thouars, Duchess of Brittany (b. 1201)
  3. 1266 - Birger jarl, Swedish statesman and founder of Stockholm (b. 1210)
  4. 1422 - King Charles VI of France (b. 1368)
  5. 1500 - Emperor Go-Tsuchimikado of Japan (b. 1442)
  6. 1505 - Paul Scriptoris, German mathematician
  7. 1558 - Julius Caesar Scaliger, Italian humanist scholar (b. 1484)
  8. 1600 - Toda Katsushige, Japanese warlord (b. 1557)
  9. 1623 - William Wade, English statesman and diplomat (b. 1546)
  10. 1662 - Henry Lawes, English composer (b. 1595)
  11. 1687 - Sir Edmund Waller, English poet (b. 1606)
  12. 1765 - Giovanni Paolo Pannini, Italian painter and architect (b. 1691)
  13. 1775 - Peyton Randolph, American president of the Continental Congress (b. 1721)
  14. 1777 - Samuel Foote, English dramatist and actor (b. 1720)
  15. 1805 - Horatio Nelson, British admiral (mortally wounded in battle) (b. 1758)
  16. 1872 - Jacques Babinet, French physicist (b. 1794)
  17. 1873 - Johann Sebastian Welhaven, Norwegian poet (b. 1807)
  18. 1896 - James Henry Greathead, British engineer (b. 1844)
  19. 1904 - Isabelle Eberhardt, explorer and writer who spent a lot of time in North Africa (b. 1877)
  20. 1931 - Arthur Schnitzler, Austrian writer (b. 1862)
  21. 1944 - Alois Kayser, German missionary to Nauru (b. 1877)
  22. 1965 - Bill Black, American musician (b. 1926)
  23. 1969 - Jack Kerouac, American novelist (b. 1922)
  24. 1969 - Waclaw Sierpinski, Polish mathematician (b. 1882)
  25. 1975 - Charles Reidpath, American athlete (b. 1887)
  26. 1978 - Anastas Mikoyan, Soviet politician (b. 1895)
  27. 1980 - Hans Asperger, Austrian psychologist (b. 1906)
  28. 1984 - François Truffaut, French film director (b. 1932)
  29. 1986 - Lionel Murphy, Australian politician and judge (b. 1922)
  30. 1992 - Jim Garrison, American attorney (b. 1921)
  31. 1995 - Shannon Hoon, American singer (Blind Melon) (b. 1967)
  32. 1995 - Jesús Blasco, Spanish comic book author (b. 1919)
  33. 1995 - Maxene Andrews, American singer (The Andrews Sisters) (b. 1916)
  34. 2003 - Fred Berry, American actor (b. 1951)
  35. 2003 - Luis A. Ferré, Governor of Puerto Rico (b. 1940)
  36. 2003 - Louise Day Hicks, American politician (b. 1916)
  37. 2003 - Elliott Smith, American musician (b. 1969)
  38. 2005 - Tara Correa-McMullen, American actress (b. 1989)