According to the National Cancer Institute, there are 4 treatments for Cancer of the Penis. Surgery is the most common and there are different types of operations. They are:

  1. Wide local excision takes out only the cancer and some normal tissue on either side.
  2. Mohs microsurgery is an operation that removes the cancer and as little normal tissue as possible. During this surgery, the doctor uses a microscope to look at the cancerous area to make sure all the cancer cells are removed.
  3. Laser surgery uses a narrow beam of light to remove cancer cells.
  4. Cryosurgery uses an instrument to freeze and destroy abnormal tissue, such as carcinoma in situ. This type of treatment is also called cryotherapy.
  5. Circumcision is an operation that removes the foreskin.
  6. Amputation of the penis is an operation that takes out all or part of the penis. It is the most common and most effective treatment of cancer of the penis. In a partial penectomy, part of the penis is taken out. In a total penectomy, the whole penis is removed. Lymph nodes in the groin may be taken out during surgery.