1. Treatment of Addison's disease involves replacing, or substituting, the hormones that the adrenal glands are not making.
  2. Cortisol is replaced orally with hydrocortisone tablets, a synthetic glucocorticoid, taken once or twice a day.
  3. If aldosterone is also deficient, it is replaced with oral doses of a mineralocorticoid called fludrocortisone acetate