As soon as your doctor suspects that you have plague, you'll need to be admitted to an isolation room in a hospital. There, you'll receive powerful antibiotics directly into your veins (intravenously) or your muscles (intramuscularly) for at least 10 days.
- Streptomycin and gentamicin are the most effective drugs against plague.
- Other alternatives include intravenous doxycycline (Vibramycin), ciprofloxacin (Cipro) and chloramphenicol (Chloromycetin).
- If you have serious complications, such as bleeding abnormalities, organ failure and respiratory distress, then respiratory support, intravenous fluids and oxygen may be necessary.
- Even if you don't have signs or symptoms, you'll need treatment with preventive, oral antibiotics for seven days after direct exposure to a person with pneumonic plague.