Most cases of whooping cough require no specific treatment. Infants and small children with other conditions such as asthma require constant monitoring which, at least for a while.
- Three macrolides, erythromycin, azithromycin and clarithromycin are used in the U.S. for treatment of Wooping Cough.
- Trimethoprim-sulfamethoxazole is generally used when a macrolide is uneffective or is contraindicated.
- Close contacts who receive appropriate antibiotics (chemoprophylaxis) during the 7–21 day incubation period may be protected from developing symptomatic disease.