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Description and Symptoms of Variant Creutzfeldt-Jakob disease
INFORMATIVE 
Tags: Creutzfeldt-Jakob disease (CJD), degenerative neurological disorder, brain disease, transmissible spongiform encephalopathies, symptoms
Creutzfeldt-Jakob disease (CJD) is a very rare and incurable degenerative neurological disorder (brain disease) that is ultimately fatal. It is the most common of the transmissible spongiform encephalopathies (TSEs).
| | The first symptom of CJD is rapidly progressive dementia, leading to memory loss, personality changes and hallucinations. |
| | This is accompanied by physical problems such as speech impairment, jerky movements (myoclonus), balance and coordination dysfunction (ataxia), changes in gait, rigid posture, and seizures. |
| | The duration of the disease varies greatly, but sporadic (non-inherited) CJD can be fatal within months or even weeks (Johnson, 1998). In most patients, these symptoms are followed by involuntary movements and the appearance of a typical diagnostic electroencephalogram tracing. |
| | The symptoms of CJD are caused by the progressive death of the brain's nerve cells, which is associated with the build-up of abnormal prion proteins. |
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