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Treatments for Primary biliary cirrhosis  
INFORMATIVE User Created List

Tags: Primary biliary cirrhosis, ductopenia, cirrhosis, liver granulomas, progressive cholestasis, end-stage liver disease, progressive obstructive jaundice, treatments

Treatment may be useful in several ways. Proper advice will ensure the elimination of potentially harmful drugs, foods, or toxins.

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  • If the patient is deficient in vitamin D, then this should be corrected. The thyroid function should be tested and, if low, treated with a thyroid hormone.
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  • Symptoms may be successfully relieved. Itching is often reduced by using cholestryramine and rifampin. Salt restriction may be effective in reducing fluid accumulation.
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  • The diet should be well-balanced. Corticosteroids have been found ineffective in most patients. The FDA has approved only URSO 250 (manufactured by Axcan Scandipharm) for use in patients with PBC. The recommended dose is 13-15 mg/kg once a day.
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  • Physicians who treat PNC patients often prescribe other ursodiol products off-label. These products include Actigall (manufactured by Novartis) and various generic formulations.

    Lister: LisaLisa
    Source: Compiled by LAL Editor

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