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Multiple myeloma Symptoms
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Tags: Multiple myeloma
Multiple myeloma Symptoms
| | Frequently, the first sign of multiple myeloma is bone pain due to bony destruction by plasma cells. The bone pain associated with myeloma can be very intense and may occur with motion or at rest. Often, narcotics, such as morphine, are required to alleviate the discomfort of the bone pain. Any bony region can be involved – often times the destructive bone changes are very advanced before any symptoms begin. The axial skeleton (vertebrae), rib cage, skull, and bones of the extremities are commonly involved in multiple myeloma. |
| | As the malignant plasma cells replace the normal blood forming elements in the marrow, anemia and fatigue may be apparent. The marrow also produces fewer platelets, blood cells which regulate clots and bleeding. As a result, multiple myeloma victims may experience bleeding gums, nosebleeds or easy bruising. Unexplained bone fractures, kidney failure, persistent infections and weight loss are other signs of the disease. Often, the disease can be found incidentally on routine blood testing. |
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