| 1. | Super Mario Bros. (40.23 million) |
| 2. | Super Mario Bros. 3 (18 million) |
| 3. | Super Mario Bros. 2 (10 million) |
| 4. | The Legend of Zelda (6.51 million) |
| 5. | Zelda II: The Adventure of Link (4.38 million) |
| 6. | Teenage Mutant Ninja Turtles (4 million) |
| 7. | Dragon Warrior III (3.8 million in Japan) |
| 8. | Dragon Warrior IV (3.1 million in Japan) |
| 9. | Golf (2.46 million in Japan) |
| 10. | Baseball (2.45 million in Japan) |
| 11. | Dragon Warrior II (2.4 million in Japan) |
| 12. | Mahjong (2.13 million in Japan) |
| 13. | Pro Yakyuu Family Stadium (2.05 million in Japan) |
| 14. | Tetris (1.81 million in Japan) |
| 15. | Duck Tales (1.67 million) |
| 16. | Ghosts 'n Goblins (1.64 million) |
| 17. | Mario Bros. (1.63 million in Japan) |
| 18. | Excitebike (1.57 million in Japan) |
| 19. | Dr. Mario (1.53 million in Japan) |
| 20. | Soccer (1.53 million in Japan) |
| 21. | F-1 Race (1.52 million in Japan) |
| 22. | Mega Man 2 (1.51 million) |
| 23. | Dragon Warrior (1.5 million in Japan) |
| 24. | Ninja Hattori Kun (1.5 million in Japan) |
| 25. | Lode Runner (1.5 million in Japan) |
| 26. | Dragon Ball Z (1.45 million in Japan) |
| 27. | 4ninuchi Mahjong (1.45 million in Japan) |
| 28. | Kung Fu Master (1.42 million in Japan) |
| 29. | Final Fantasy III (1.4 million in Japan) |
| 30. | Pro Yakyuu Family Stadium '87 (1.3 million in Japan) |
| 31. | Xevious (1.26 million in Japan) |
| 32. | Gegege no Kitaro: Youkai Daimakyou (1.25 million in Japan) |
| 33. | Tennis (1.21 million in Japan) |
| 34. | Twin Bee (1.2 million in Japan) |
| 35. | Ganbare Goemon! Karakuri Douchuu (1.2 million in Japan) |
| 36. | Chip 'n Dale Rescue Rangers (1.2 million) |
| 37. | Dragon Ball Z II: Gekigami Freeza (1.15 million in Japan) |
| 38. | Doreamon (1.15 million in Japan) |
| 39. | Commando (1.14 million) |
| 40. | Kid Icarus (1.09 million in Japan) |
| 41. | Pro Yakyuu Family Stadium '88 (1.08 million in Japan) |
| 42. | Mega Man 3 (1.08 million) |
| 43. | Famicom Jump Eiyuu Retsuden (1.06 million in Japan) |
| 44. | Kinnikuman: Muscle Tag Match (1.05 million in Japan) |
| 45. | Adventure Island (1.05 million in Japan) |
| 46. | Metal Gear (1 million in US) |
| 47. | Gradius (1 million in Japan) |