| | Alexander Lemming from The Beano, named after Alexander Fleming |
| | Ann-Margrock Flintstones character after actress Ann-Margret |
| | Arnie Pie from The Simpsons is named after Ernie Pyle. |
| | Arpine Lusène, named after Arsène Lupin, a fictional character from Maurice Leblanc. |
| | Baby Crockett, from The Beezer comic – Davy Crockett |
| | Baby Face Finlayson, from The Beano comic – Baby Face Nelson |
| | Buzz Lightyear from Toy Story is named after astronaut Buzz Aldrin |
| | Calamity James from The Beano comic – Calamity Jane |
| | Calvin from Calvin and Hobbes – John Calvin, 16th century theologian |
| | Hobbes from Calvin and Hobbes – Thomas Hobbes, 17th century philosopher |
| | Cary Granite - Flintstones character after actor Cary Grant |
| | Casey Strangle appeared on The Flintstones, named after Casey Stengel. |
| | Char Aznable (Mobile Suit Gundam through Char's Counterattack). Rumored to be named after French lounge singer Charles Aznavour. |
| | Clark Gravel - Flintstones character named after actor Clark Gable. |
| | Donatello, the second youngest of the ninja turtle brothers from TMNT, was named after the Italian Renaissance artist and sculptor, Donatello |
| | Egroeg Sacul, Star Tours at the Disney-MGM Studios, named after Star Wars creator George Lucas. Egroeg Sacul is George Lucas spelled backwards. |
| | Foghorn Leghorn, Warner Brothers cartoons – Senator Claghorn, regular character on the Fred Allen radio show |
| | Frankie Stein, from the Wham!, Shiver and Shake, Whoopee! and Monster Fun comics. – Frankenstein |
| | Fred Bonaparte, from the game Psychonauts, named after his apparent ancestor, Napoleon Bonaparte. |
| | Dewey, one of "Huey, Dewey and Louie" – Thomas Edmund Dewey, American politician |
| | Gloria Von Gouten, from the game Psychonauts, named after the famous actor, Gloria Swanson. |
| | Helga G. Pataki of "Hey Arnold!", named after former governor George Pataki. |
| | Huey Freeman from The Boondocks is named after Huey P. Newton |
| | Huey, one of "Huey, Dewey and Louie" – Huey Pierce Long, American politician |
| | Hitmonlee from Pokémon – Bruce Lee, martial artist |
| | Hitmonchan from Pokémon – Jackie Chan, martial artist |
| | Hohenheim of Light, from Fullmetal Alchemist - Paracelsus, sixteenth-century alchemist, whose real name was Theophrastus Van Hohenheim |
| | Huckleberry Hound - Huckleberry Finn, The Adventures of Huckleberry Finn |
| | Ivy the Terrible, from The Beano comic – Ivan the Terrible. |
| | Jane Roberts from The Little Wolf and the Bad Little Girl – person of the same name. |
| | Jesse and James from Pokémon are named after Jesse James. |
| | Jimmy Darrock, Flinstones character named after singer James Darren. |
| | John D. Rockerduck, named after John D. Rockefeller. |
| | Jules and Verne, the sons of Doctor Emmett Brown in Back to the Future: The Animated Series, are named after Jules Verne. |
| | Kill Rates, co founder of Mocksoft, named after Bill Gates, co founder of Microsoft. |
| | The Koopalings are named after various famous people. |
| | Leonardo, the oldest of the ninja turtle brothers from TMNT, was named after the great Italian Renaissance artist and scientist, Leonardo da Vinci |
| | Leo Ferocious appeared on The Flintstones, named after Leo Durocher. |
| | Ludwig Von Drake, named after Ludwig van Beethoven. |
| | Marge Bouvier Simpson, named after Jacqueline Lee Bouvier Kennedy Onassis, former First Lady of the United States, widow to John F Kennedy. |
| | Michelangelo, the youngest of the ninja turtle brothers from TMNT, was named after the great Italian Renaissance artist and sculptor, Michelangelo Buonarotti |
| | Milhouse Van Houten from The Simpsons is named after Richard Milhous Nixon, see BBC Simpson's page |
| | Mickey Mouse, Mickey Rooney claims it was named after him (see cartoon character's page for the official origin). |
| | Morlocks - in Marvel Comics, a group of mutants naming themselves after the futuristic race in H.G. Wells' The Time Machine |
| | Mr. Hook from The Little Wolf and the Bad Little Girl – Captain Hook, fictional character in J.M. Barrie's Peter Pan. |
| | Nemo from the movie Finding Nemo – Captain Nemo, fictional character in Jules Verne's novels: 20,000 Leagues under the Sea and The Mysterious Island. |
| | Nero (Flemish Comics), Belgian comic character by Marc Sleen is named after the Roman emperor Nero. |
| | Oscar from Cerebus – named after poet and playwright Oscar Wilde. |
| | Pepe Le Pew, French skunk in Warner Brothers cartoons – Pepe le Moko, fictional character from the novel and movies of the same name |
| | Philip J. Fry, from Futurama – Phil Hartman, voice actor |
| | Hubert Farnsworth from Futurama – Philo Farnsworth |
| | Scrooge McDuck – Ebenezer Scrooge, fictional character in Charles Dickens' A Christmas Carol |
| | Seymour Skinner is named after B.F. Skinner. |
| | Raphael, the second oldest of the ninja turtle brothers from TMNT, was named after the Italian Renaissance artist and sculptor, Raphael Sanzio |
| | Richard the Lion, from The Beano comic – Richard the Lionheart |
| | Rip Van Wink, from The Beano comic – Rip van Winkle |
| | Sigmund (Dutch comics character), named after Sigmund Freud |
| | Stony Curtis - Flintstones character after actor Tony Curtis |
| | Tony Zucco - Rumored to be named after the actor George Zucco |
| | Sweeny Toddler, from the Shiver and Shake, Whoopee! and Buster comics – Named after Sweeney Todd |
| | Tycho Brahe, from Penny Arcade – Tycho Brahe, sixteenth-century astronomer |
| | Yogi Bear – Yogi Berra, baseball player |
| | Yensid Fantasia named after Walt Disney. Yensid is Disney spelled backwards. |
| | The Teenage Mutant Ninja Turtles are each named for a Renaissance painter - Raphael, Michelangelo, Donatello, and Leonardo. |
| | Victor and Hugo, from The Hunchback of Notre Dame (Disney film) - Named after Victor Hugo, author of The Hunchback of Notre Dame |
| | Wolfgang from Hey Arnold! - Wolfgang Amadeus Mozart |
| | Ludvig from Hey Arnold! - Ludwig van Beethoven |
| | Rock Lee from Naruto is named after Bruce Lee. |